Protriptyline Hydrochloride
Protriptyline Hydrochloride is a tricyclic secondary amine with antidepressant property. Protriptyline hydrochloride blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. Protriptyline does not block dopamine transport but may have an indirect dopamine-facilitating effect through interactions of increased peri-synaptic abundance of norepinephrine, particularly in the cerebral cortex, where adrenergic terminals exceed dopaminergic terminals. This results in elevation of mood and behavioral activity. In addition, this agent exhibits anticholinergic activity.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1099 |
| CAS # | 1225-55-4 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Protriptyline Hydrochloride; Concordin; Maximed; Triptyl; Protriptyline HCl; Triptil hydrochloride; Hydrochloride, Protriptyline; Odyssey Brand of Protriptyline Hydrochloride; Protriptyline; Protriptyline Hydrochloride ; Vivactil; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H22ClN |
| Molecular Weight | 299.84 |
| Elemental Analysis | C, 76.11; H, 7.40; Cl, 11.82; N, 4.67 |
| IUPAC/Chemical Name | 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine;hydrochloride |
| InChi Key | OGQDIIKRQRZXJH-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H |
| SMILES Code | CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |