Facinicline HCl
Facinicline, also known as RG-3487, R-3487 or MEM-3454, is a partial agonist of the nicotinic alpha-7 (α7) receptor that was being co-developed by Roche for the oral treatment of Alzheimer's.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1512 |
| CAS # | 677305-02-1(HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Facinicline HCl, Facinicline hydrochloride; RG-3487; RG 3487; RG3487; R-3487; R 3487; R3487; RO-5313534; RO 5313534; RO5313534; MEM3454; MEM 3454; MEM-3454; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H19ClN4O |
| Exact Mass | 306.1247 |
| Molecular Weight | 306.794 |
| Elemental Analysis | C, 58.73; H, 6.24; Cl, 11.55; N, 18.26; O, 5.21 |
| IUPAC/Chemical Name | N-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-1H-indazole-3-carboxamide hydrochloride |
| InChi Key | CMRLNEYJEPELSM-BTQNPOSSSA-N |
| InChi Code | InChI=1S/C15H18N4O.ClH/c20-15(14-11-3-1-2-4-12(11)17-18-14)16-13-9-19-7-5-10(13)6-8-19;/h1-4,10,13H,5-9H2,(H,16,20)(H,17,18);1H/t13-;/m1./s1 |
| SMILES Code | O=C(C1=NNC2=C1C=CC=C2)N[C@@H]3CN4CCC3CC4.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |