PNU282987 HCl
PNU282987 is a drug that acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors. In animal studies, it shows nootropic effects, and derivatives may be useful in the treatment of schizophrenia, although PNU-282,987 is not suitable for use in humans because of excessive inhibition of the hERG antitarget.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1654 |
| CAS # | 123464-89-1 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | PNU282987; PNU-282987; PNU 282987; PNU282,987; PNU-282,987; PNU 282,987; PNU282987 HCl; PNU282987 hydrochloride |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C14H18Cl2N2O |
| Molecular Weight | 301.211 |
| Elemental Analysis | C, 55.83; H, 6.02; Cl, 23.54; N, 9.30; O, 5.31 |
| IUPAC/Chemical Name | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chloro-benzamide monohydrochloride |
| InChi Key | HSEQUIRZHDYOIX-ZOWNYOTGSA-N |
| InChi Code | InChI=1S/C14H17ClN2O.ClH/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17;/h1-4,10,13H,5-9H2,(H,16,18);1H/t13-;/m0./s1 |
| SMILES Code | O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |