Coluracetam
Coluracetam, also known as BCI-540; MKC-231, is a AMPA receptor agonist potentially for the treatment of major depression and anxiety. MKC-231 antagonizes phencyclidine-induced behavioral deficits and reduction in septal cholinergic neurons in rats. MKC-231 ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD101 |
| CAS # | 135463-81-9 |
| Pricing | Customizable size, Inquiry |
| Synonym | Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H23N3O3 |
| Exact Mass | 341.1739 |
| Molecular Weight | 341.411 |
| Elemental Analysis | C, 66.84; H, 6.79; N, 12.31; O, 14.06 |
| IUPAC/Chemical Name | 2-(2-Oxypyrrolidin-1-yl)-N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro(2,3-b)quinolin-4-yl)acetoamide |
| InChi Key | PSPGQHXMUKWNDI-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23) |
| SMILES Code | O=C(NC1=C2C(OC(C)=C2C)=NC3=C1CCCC3)CN4C(CCC4)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |