Brofaromine Hydrochloride
Brofaromine Hydrochloride is a reversible inhibitor of monoamine oxidase A and acts on epinephrine , norepinephrine, serotonin, and dopamine. The compound was primarily researched in the treatment of depression and anxiety. Brofaromine also acts as a serotonin reuptake inhibitor, and its dual pharmacologic effects offered promise in the treatment of a wide spectrum of depressed patients while producing less severe anticholinergic side effects in comparison with older standard drugs like the tricyclic antidepressants. Unlike standard MAOIs, possible side effects do not include cardiovascular complications (hypertension) with encephalopathy, liver toxicity or hyperthermia.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD108 |
| CAS # | 63638-90-4 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Brofaromine Hydrochloride; Brofaromine HCl; CGP-11305A; CGP-11305A. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C14H17BrClNO2 |
| Exact Mass | 345.01312 |
| Molecular Weight | 346.65 |
| Elemental Analysis | C, 48.51; H, 4.94; Br, 23.05; Cl, 10.23; N, 4.04; O, 9.23 |
| IUPAC/Chemical Name | 4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine hydrochloride |
| InChi Key | PUYKEOGYPYITCW-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C14H16BrNO2.ClH/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11;/h6-9,16H,2-5H2,1H3;1H |
| SMILES Code | c12c(c(cc(c2)OC)Br)oc(c1)C1CCNCC1.Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |