Metyrapone
Metyrapone is a drug used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). It blocks cortisol synthesis by reversibly inhibiting steroid 11β-hydroxylase. This stimulates ACTH secretion, which in turn increases plasma 11-deoxycortisol levels.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD998 |
| CAS # | 54-36-4 |
| Pricing | Customizable size, Inquiry |
| Synonym | Metyrapone, Metopirone, SU 4885, Methbipyranone, Methopyrapone |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C14H14N2O |
| Exact Mass | 226.1106 |
| Molecular Weight | 226.2738 |
| Elemental Analysis | C, 74.31; H, 6.24; N, 12.38; O, 7.07 |
| IUPAC/Chemical Name | 2-methyl-1,2-dipyridin-3-ylpropan-1-one |
| InChi Key | FJLBFSROUSIWMA-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3 |
| SMILES Code | CC(C1=CC=CN=C1)(C)C(C2=CC=CN=C2)=O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |