rel-Zotatifin
Supplier | MedChemExpress |
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Product # | HY-112163A-5 mg |
CAS # | 2098191-54-7 |
Pricing | 5 mg, USD $1850.0 |
Biological Activity | rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex[1]. |
Synonyms | rel-eFT226 |
MWt | 487.55 |
Formula | C₂₈H₂₉N₃O₅ |