rel-Zotatifin

Supplier MedChemExpress
Product # HY-112163A-5 mg
CAS # 2098191-54-7
Pricing 5 mg, USD $1850.0
Biological Activity rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex[1].
Synonyms rel-eFT226
MWt 487.55
Formula C₂₈H₂₉N₃O₅
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