Olesoxime
Olesoxime, also known as TRO-19622 and RG6083, is an experimental neuroprotective drug. Olesoxime has a cholesterol-like structure and displays neuroprotective properties. Preclinical studies have demonstrated that the compound promotes the function and survival of neurons and other cell types under disease-relevant stress conditions through interactions with the mitochondrial permeability transition pore (mPTP).
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD502 |
| CAS # | 22033-87-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | TRO-19622; TRO19622; TRO19622; RG6083; RG 6083; RG-6083; NSC 21311; NSC-21311; NSC21311; Olesoxime |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C27H45NO |
| Exact Mass | 399.3501 |
| Molecular Weight | 399.663 |
| Elemental Analysis | C, 81.14; H, 11.35; N, 3.50; O, 4.00 |
| IUPAC/Chemical Name | (8S,9S,10R,13R,14S,17R,E)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one oxime |
| InChi Key | QNTASHOAVRSLMD-SIWSWZRQSA-N |
| InChi Code | InChI=1S/C27H45NO/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28-29)13-15-26(20,4)25(22)14-16-27(23,24)5/h17-19,22-25,29H,6-16H2,1-5H3/b28-21+/t19-,22+,23-,24+,25+,26+,27-/m1/s1 |
| SMILES Code | O/N=C1CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@]4([H])[C@]3([H])CCC2=C\1 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |