Lexibulin

Lexibulin (CYT-997) is a potent and orally active tubulin polymerization inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells.

• Supplier: CD BioSciences
• Product #: CIA-11329