Mosapramine
Mosapramine, also known as Clospipramine and Y-516, is a dopamine D2-receptor antagonist used for the treatment of schizophrenia. The affinities of mosapramine for D4 receptors is 8 times higher than that of clozapine, and the affinity for D3 receptors is 40 times higher than that of raclopride.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1595 |
| CAS # | 89419-40-9 |
| Pricing | Customizable size, Inquiry |
| Synonym | Mosapramine; Y-516; Y 516; Y516; Cremin; Clospipramine |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C28H35ClN4O |
| Exact Mass | 478.2499 |
| Molecular Weight | 479.065 |
| Elemental Analysis | C, 70.20; H, 7.36; Cl, 7.40; N, 11.70; O, 3.34 |
| IUPAC/Chemical Name | 1'-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one |
| InChi Key | PXUIZULXJVRBPC-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C28H35ClN4O/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34) |
| SMILES Code | O=C1NC2CCCCN2C13CCN(CCCN4C5=CC(Cl)=CC=C5CCC6=CC=CC=C64)CC3 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |