Tacrolimus (FK506)
Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S5003 |
| Sku # | S5003-10mM/1mL |
| Pricing | 10mM/1mL, $140.00 |
Citations for this product:
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bioRxiv - Molecular Biology 2020Quote: ... NVP-BVU972 (S2761), FK-506 (Tacrolimus, S5003) were obtained from Selleck Chemicals, JNK Inhibitor V (420129 ...