Ro 60-0175 fumarate
Ro60-0175 is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Ro60-0175 acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD365 |
| CAS # | 169675-09-6 (fumarate) |
| Pricing | Customizable size, Inquiry |
| Synonym | Ro 60-0175 fumarate; Ro60-0175; Ro-60-0175; Ro 60-0175; Ro600175; Ro-600175; Ro 600175; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C15H16ClFN2O4 |
| Molecular Weight | 342.75 |
| Elemental Analysis | C, 52.56; H, 4.71; Cl, 10.34; F, 5.54; N, 8.17; O, 18.67 |
| IUPAC/Chemical Name | (S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine fumarate |
| InChi Key | CEPHEXXZGQBXGT-XZTIXWOLSA-N |
| InChi Code | InChI=1S/C11H12ClFN2.C4H4O4/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15;5-3(6)1-2-4(7)8/h2-5,7H,6,14H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t7-;/m0./s1 |
| SMILES Code | C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=C/C(=O)O)\C(=O)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO and water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |