Carphenazine Dimaleate
Carfenazine, also known as WY-2445, or carphenazine (BAN), also known as carphenazine maleate (USAN) (brand name Proketazine; former developmental code name NSC-71755), is an antipsychotic and tranquilizer of the phenothiazine group that was withdrawn from the market. Carphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1465 |
| CAS # | 2975-34-0 (maleate) |
| Pricing | Customizable size, Inquiry |
| Synonym | Carphenazine Dimaleate; Proketazine; Proketazine; Procethazine; carphenazine; NSC 71755; WY2445; WY-2445; WY 2445; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C32H39N3O10S |
| Molecular Weight | 657.735 |
| Elemental Analysis | C, 58.44; H, 5.98; N, 6.39; O, 24.32; S, 4.87 |
| IUPAC/Chemical Name | 1-(10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)-10H-phenothiazin-2-yl)propan-1-one dimaleate |
| InChi Key | TVPJGGZLZLUPOB-SPIKMXEPSA-N |
| InChi Code | InChI=1S/C24H31N3O2S.2C4H4O4/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28;2*5-3(6)1-2-4(7)8/h3-4,6-9,18,28H,2,5,10-17H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1- |
| SMILES Code | CCC(=O)C1=CC2=C(SC3=CC=CC=C3N2CCCN4CCN(CC4)CCO)C=C1.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |