N-Desmethylclozapine

Supplier MedChemExpress
Product # HY-G0021-5 mg
CAS # 6104-71-8
Pricing 5 mg, USD $96.0
Synonyms Norclozapine; Desmethylclozapine; Normethylclozapine
MWt 312.8
Formula C₁₇H₁₇ClN₄
Biological Activity N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist[1][2].
Purity 99.72%
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