Tacrolimus (FK506)
Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.
Supplier | Selleck Chemicals |
---|---|
Product # | S5003 |
Sku # | S5003-1g |
Pricing | 1g, $670.00 |
Citations for this product:
-
bioRxiv - Molecular Biology 2020Quote: ... NVP-BVU972 (S2761), FK-506 (Tacrolimus, S5003) were obtained from Selleck Chemicals, JNK Inhibitor V (420129 ...