Buparlisib (BKM120)
Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
Supplier | Selleck Chemicals |
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Product # | S2247 |
Sku # | S2247-5mg |
Pricing | 5mg, $117.00 |
Citations for this product:
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bioRxiv - Pathology 2021Quote: ... Buparlisib 1 µM (S2247, Selleck Chemicals Llc) or Taselisib 1 µM (S7103 ...