Zuclopenthixol dihydrochloride
Zuclopenthixol, also known as Cisordinol, Clopixol, Acuphase, zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1962 by Lundbeck. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. Zuclopenthixol has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but no affinity for cholinergic muscarine receptors. It has weak histamine (H1) receptor affinity and no α2-adrenoceptor blocking activity.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1769 |
| CAS # | 58045-23-1 (HCl) |
| Pricing | Customizable size, Inquiry |
| Synonym | Zuclopenthixol dihydrochloride; Zuclopenthixol HCl; alpha-Clopenthixol; Cisordinol; Clopenthixol; Zuclopenthixol; Cisordinol; cis-Clopenthixol; Clopixol; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C22H27Cl3N2OS |
| Exact Mass | 472.09 |
| Molecular Weight | 473.88 |
| Elemental Analysis | C, 55.76; H, 5.74; Cl, 22.44; N, 5.91; O, 3.38; S, 6.77 |
| IUPAC/Chemical Name | 2-[4-[(3Z)-3-(2-Chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol dihydrochloride |
| InChi Key | LPWNZMIBFHMYMX-MHKBYHAFSA-N |
| InChi Code | InChI=1S/C22H25ClN2OS.2ClH/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26;;/h1-2,4-8,16,26H,3,9-15H2;2*1H/b18-5-;; |
| SMILES Code | ClC1=CC(/C2=C\CCN3CCN(CCO)CC3)=C(SC4=C2C=CC=C4)C=C1.[H]Cl.[H]Cl |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |