7α,25-Dihydroxycholesterol
Supplier | MedChemExpress |
---|---|
Product # | HY-113962-5 mg |
CAS # | 64907-22-8 |
Pricing | 5 mg, USD $680.0 |
Synonyms | 7α,25-OHC |
MWt | 418.65 |
Formula | C₂₇H₄₆O₃ |
Biological Activity | 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2]. |
Purity | ≥99.0% |