7α,25-Dihydroxycholesterol

Supplier MedChemExpress
Product # HY-113962-5 mg
CAS # 64907-22-8
Pricing 5 mg, USD $680.0
Synonyms 7α,25-OHC
MWt 418.65
Formula C₂₇H₄₆O₃
Biological Activity 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2].
Purity ≥99.0%
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