Talazoparib (BMN 673)
Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S7048 |
| Sku # | S7048-10mM/1mL |
| Pricing | 10mM/1mL, $97.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2020Quote: ... talazoparib (Selleck Chemicals, S7048), camptothecin (Cayman Chemicals ...
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bioRxiv - Cancer Biology 2021Quote: ... Talazoparib (Selleck Chemicals; #S7048), 5-Iodo-2’-deoxyuridine (IdU ...
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bioRxiv - Cancer Biology 2023Quote: ... LCL were treated with PARP1 inhibitor BMN-673 (Talazoparib, LT-673; Selleck Chemicals, Cat. No. S7048) for 72 hours (h) ...
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bioRxiv - Cancer Biology 2023Quote: ... BMN-673 (0.33 mg/Kg, cat. No. S7048, Selleck Chemicals, Houston, TX, USA) or vehicle (10% DMAc ...