Fenobam
Fenobam is a a potent and selective negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5. Fenobam displays inverse agonist properties; blocks mGluR5 constitutive activity in vitro (IC50 = 87 nM, slightly weaker than MPEP). Fenobam has been used as a lead compound for the development of a range of newer mGluR5 antagonists.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD203 |
| CAS # | 57653-26-6 |
| Pricing | Customizable size, Inquiry |
| Synonym | Fenobam; NPL-2009; NPL2009; NPL 2009 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C11H11ClN4O2 |
| Exact Mass | 266.0571 |
| Molecular Weight | 266.685 |
| Elemental Analysis | C, 49.54; H, 4.16; Cl, 13.29; N, 21.01; O, 12.00 |
| IUPAC/Chemical Name | 1-(3-chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea |
| InChi Key | DWPQODZAOSWNHB-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C11H11ClN4O2/c1-16-6-9(17)14-10(16)15-11(18)13-8-4-2-3-7(12)5-8/h2-5H,6H2,1H3,(H2,13,14,15,17,18) |
| SMILES Code | O=C(NC(N(C)C1)=NC1=O)NC2=CC=CC(Cl)=C2 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |