Sorbitan Trioleate(span 85)
This product is an amber viscous liquid.
Supplier | CD Formulation |
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Product # | PE-0431 |
Pricing | , Inquire for price |
product1 | Pharmaceutical Excipients |
Molecular Formula | C60H108O8 |
Molecular Weight | 957.49 |
Applications | This product is used as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer, etc. |
Safety | Sorbitan ester is widely used in cosmetics, food, oral and topical pharmaceutical preparations, and is generally considered non-toxic and non-irritating. However, there have been occasional reports of allergic reactions to topical agents containing sorbitan cilexetil. Sorbitan ester emits irritating fumes when heated to decomposition temperature. |
Incompatibilities | / |
Synonyms | Ablunol S-85; Arlacel 85; Crill 45; Glycomul TO; Hodag STO; Liposorb TO; Montane 85; Nissan Nonion OP-85R; Protachem STO; Protesorb STO; S-Maz 85K; Sorbester P37; sorbitani trioleas; Span 85; Tego STO |
CAS Number | 26266-58-0 |
Category | Surfactant; Emulsifier; Lubricant; Humectants; Dispersant; Thickener; Defoamer |
UNII | QE6F49RPJ1 |
Chemical Name | (Z, Z, Z)-Sorbitan tri-9-octadecenoate |
Grade | Pharmceutical Excipients |
Administration route | Inhalation; Nasal Administration; Oral; Topical |
Dosage Form | Oral inhalation, topical formulation |
Stability and Storage Conditions | Gradually saponified under strong acid or strong base; stable in weak acid or weak base. It should be packed in an airtight container and stored in a cool and dry place. |
Source and Preparation | This product is a mixture of sorbitol mono-dehydrate, di-dehydrate and three molecules of oleic acid. Its production method is to firstly dehydrate sorbitol at 150-152°C, and esterify it with three molecules of oleic acid under the catalysis of sodium bicarbonate. Or it can be prepared by direct esterification of α-sorbitol and three molecules of oleic acid at 180-280°C. |