ABT-239

ABT-239 is an H3-receptor inverse agonist developed by Abbott. It has stimulant and nootropic effects, and has been investigated as a treatment for ADHD, Alzheimer's disease, and schizophrenia. ABT-239 is more active at the human H3 receptor than comparable agents such as thioperamide, ciproxifan, and cipralisant.
Supplier Ace Therapeutics
Product # SMD1360
CAS # 460746-46-7
Pricing Customizable size, Inquiry
Synonym ABT-239; ABT 239; ABT239;
Product Category Lab-use Small Molecule Drugs
Chemical Formula C22H22N2O
Exact Mass 330.17321
Molecular Weight 330.42
Elemental Analysis C, 79.97; H, 6.71; N, 8.48; O, 4.84
IUPAC/Chemical Name
  • 4-(2-{2-[(2R)-2-Methylpyrrolidin-1-yl]ethyl}-
  • benzofuran-5-yl)benzonitrile
InChi Key KFHYZKCRXNRKRC-MRXNPFEDSA-N
InChi Code InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3/t16-/m1/s1
SMILES Code N#CC1=CC=C(C2=CC=C(OC(CCN3[C@H](C)CCC3)=C4)C4=C2)C=C1
Appearance Solid powder
Purity >98% (or refer to the Certificate of Analysis)
Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility Soluble in DMSO, not in water
Shelf Life >2 years if stored properly
Drug Formulation This drug may be formulated in DMSO
Stock Solution Storage 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code 2934.99.9001
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