Nefazodone
Nefazodone is an antidepressant. Its chemical structure is unrelated to selective serotonin reuptake inhibitors, tricyclics, tetracyclics, or monoamine oxidase inhibitors (MAOI). Nefazodone has low affinity for the serotonin (200 nM), norepinephrine (360 nM), and dopamine (360 nM) transporters, and therefore acts as a weak serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD314 |
| CAS # | 83366-66-9 |
| Pricing | Customizable size, Inquiry |
| Synonym | Nefazodone, Dutonin, Nefadar, Serzone |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C25H32ClN5O2 |
| Exact Mass | 469.2245 |
| Molecular Weight | 470.0069 |
| Elemental Analysis | C, 63.89; H, 6.86; Cl, 7.54; N, 14.90; O, 6.81 |
| IUPAC/Chemical Name | 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one |
| InChi Key | VRBKIVRKKCLPHA-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3 |
| SMILES Code | O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Depression |
| Availability | 2 Weeks |