AZD8926
AZD8926 is a potent and selective GSK3β inhibitor (glycogen synthase kinase-3β). AZD8926 has potential for treating several CNS disorders, such as Alzheimer’s disease (AD), schizophrenia, and chronic as well as acute neurodegenerative diseases.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1415 |
| CAS # | 933785-68-3 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | AZD8926; AZD-8926; AZD 8926. |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C25H27F4N7O2 |
| Exact Mass | 533.2162 |
| Molecular Weight | 533.5316 |
| Elemental Analysis | C, 56.28; H, 5.10; F, 14.24; N, 18.38; O, 6.00 |
| IUPAC/Chemical Name | (4-((5-fluoro-4-(1-(tetrahydro-2H-pyran-4-yl)-2-(trifluoromethyl)-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone |
| InChi Key | JKLMQKZMMRJQCK-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C25H27F4N7O2/c1-34-8-10-35(11-9-34)22(37)16-2-4-17(5-3-16)32-24-31-14-19(26)21(33-24)20-15-30-23(25(27,28)29)36(20)18-6-12-38-13-7-18/h2-5,14-15,18H,6-13H2,1H3,(H,31,32,33) |
| SMILES Code | O=C(C1=CC=C(NC2=NC=C(F)C(C3=CN=C(C(F)(F)F)N3C4CCOCC4)=N2)C=C1)N5CCN(C)CC5 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |