Luzindole
Luzindole, also known as N-0774, and N-acetyl-2-benzyltryptamine, is a melatonin receptor antagonist that preferentially targets MT1B over MT1A (Ki values are = 10-27 and 158-513 nM, respectively). Luzindole induces the activation of cellular stress responses and decreases viability of rat pancreatic stellate cells. Luzindole inhibits the transient outward K+ current in rat cerebellar granule cells. Luzindole suppresses experimental autoimmune encephalomyelitis.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD960 |
| CAS # | 117946-91-5 (free base) |
| Pricing | Customizable size, Inquiry |
| Synonym | Luzindole, N-0774, N0774, N 0774, N-acetyl-2-benzyltryptamine |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C19H20N2O |
| Exact Mass | 292.1576 |
| Molecular Weight | 292.382 |
| Elemental Analysis | C, 78.05; H, 6.90; N, 9.58; O, 5.47 |
| IUPAC/Chemical Name | N-Acetyl-2-benzyltryptamine |
| InChi Key | WVVXBPKOIZGVNS-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22) |
| SMILES Code | O=C(NCCC1=C(CC2=CC=CC=C2)NC3=CC=CC=C13)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |