Levcycloserine
Blocks sphingosine biosynthesis by inhibition of ketosphinganine synthetase. Cytotoxicity toward neuroblastoma and medulloblastoma cells mediated by suppression of ganglioside synthesis.[1]
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.
L-cycloserine is a potent inhibitor of serine palmitoyltransferase, the first step of sphingolipid synthesis.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD274 |
| CAS # | 339-72-0 |
| Pricing | Customizable size, Inquiry |
| Synonym | Levcycloserine; Cyclo-L-serine; Levcicloserina; L-Oxamicina; BRN 0080799; |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C3H6N2O2 |
| Exact Mass | 102.0429 |
| Molecular Weight | 102.093 |
| Elemental Analysis | C, 35.29; H, 5.92; N, 27.44; O, 31.34 |
| IUPAC/Chemical Name | (S)-4-aminoisoxazolidin-3-one |
| InChi Key | DYDCUQKUCUHJBH-REOHCLBHSA-N |
| InChi Code | InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1 |
| SMILES Code | O=C1NOC[C@@H]1N |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Class-2 | Schizophrenia |
| Availability | 2 Weeks |