PH-002
PH-002 is a novel inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that restores mitochondrial cytochrome c oxidase subunit 1 levels, rescuing impairments of mitochondrial motility and neurite outgrowth.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1635 |
| CAS # | 1311174-68-1 |
| Pricing | Customizable size, Inquiry |
| Synonym | PH-002; PH 002; PH002 |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C27H33N5O4 |
| Exact Mass | 491.2533 |
| Molecular Weight | 491.592 |
| Elemental Analysis | C, 65.97; H, 6.77; N, 14.25; O, 13.02 |
| IUPAC/Chemical Name | 4-[[4-[[2-(3,4-Dihydro-3-methyl-4-oxo-1-phthalazinyl)acetyl]amino]phenyl]methyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester |
| InChi Key | GSXXTLWPQMHHDJ-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C27H33N5O4/c1-27(2,3)36-26(35)32-15-13-31(14-16-32)18-19-9-11-20(12-10-19)28-24(33)17-23-21-7-5-6-8-22(21)25(34)30(4)29-23/h5-12H,13-18H2,1-4H3,(H,28,33) |
| SMILES Code | O=C(N1CCN(CC2=CC=C(NC(CC3=NN(C)C(C4=C3C=CC=C4)=O)=O)C=C2)CC1)OC(C)(C)C |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |
| Availability | 2 Weeks |