| Supplier |
Creative Peptides |
| Product # |
R1915 |
| CAS # |
2873-36-1 |
| Pricing |
Inquire
|
| Synonyms |
cyclo(Leu-Pro); Cyclo(L-leucyl-L-prolyl)
|
| MolecularFormula |
C11H18N2O2
|
| MolecularWeight |
210.3
|
| Storage |
Store at -20°C
|
| ShippingCondition |
- Evaluation sample solution : ship with blue ice
- All other available size: ship with RT , or blue ice upon request
|
| Explanation |
Cyclo(-Leu-Pro) is a cyclic dipeptide containing leucine and proline. Cyclo(L-Leu-L-Pro) is a homodetic cyclic peptide composed from leucyl and prolyl residues. It has a role as a marine metabolite and a bacterial metabolite. It is a dipeptide, a homodetic cyclic peptide and a pyrrolopyrazine.
|
| ChemicalName |
(3S,8aS)-3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
|
| Application |
Antimicrobial & Antiviral Peptides; Obesity Research
|
| Activity |
Antimicrobial cyclopeptide
|
| InChI |
InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)/t8-,9-/m0/s1
|
| InChIKey |
SZJNCZMRZAUNQT-IUCAKERBSA-N
|
| CanonicalSMILES |
CC(C)CC1C(=O)N2CCCC2C(=O)N1
|
| Solubility |
Soluble in DMSO
|
| IsomericSMILES |
CC(C)C[C@H]1C(=O)N2CCC[C@H]2C(=O)N1
|
| BiologicalActivity |
Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry.
|