Tyrosine-Protein Kinase Fgr (FGR) Antibody
FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta 2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Supplier | Abbexa Ltd. |
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Product # | abx010780-100UL |
Pricing | 100 µl USD $420.5 |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Host | Mouse |
Tested Applications | ELISA, WB, IHC |
UniProt Primary AC | P09769 |
Dry Ice | No |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |