Carboplatin
Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
| Supplier | Selleck Chemicals |
|---|---|
| Product # | S1215 |
| Sku # | S1215-50mg |
| Pricing | 50mg, $77.00 |
Citations for this product:
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bioRxiv - Cancer Biology 2020Quote: ... and carboplatin (Selleck Chemicals S1215) at 1 µM and 1.6 µM respectively ...
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bioRxiv - Cancer Biology 2020Quote: ... and carboplatin (Selleck Chemicals S1215) at 1µM and 1.6µM respectively was measured by an propidium iodine incorporation technique using a ADAM-sHIT automated cell counter (NanoEnTek ...
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bioRxiv - Cancer Biology 2022Quote: ... carboplatin (final conc. at 50-100uM, Selleck Chemicals, Houston TX, S1215), paclitaxel (final conc ...
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bioRxiv - Cancer Biology 2022Quote: ... Cisplatin (Cat. # S1166) and Carboplatin (Cat. # S1215) were purchased from Selleck Chemicals (Houston, TX).
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bioRxiv - Cancer Biology 2024Quote: ... carboplatin (MedChemExpress, HY-17393, Selleck Chemicals, S1215, Houston, TX, USA) was dissolved in H2O and stable drugs were stored at -20°C in the dark ...