Sacubitril/Valsartan
Supplier | MedChemExpress |
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Product # | HY-18204A-5 mg |
CAS # | 936623-90-4 |
Pricing | 5 mg, USD $70.0 |
Synonyms | LCZ696 |
MWt | 957.99 |
Formula | C₄₈H₆₀N₆Na₃O₁₀.₅ |
Biological Activity | Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure[1][2][3]. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis[4]. |
Purity | ≥99.0% |