Necrosulfonamide
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-100573-10 mg |
| CAS # | 1360614-48-7 |
| Pricing | 10 mg, USD $96.0 |
| Biological Activity | Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during the induction of necrosis[1]. |
| Purity | ≥98.0% |
| MWt | 461.47 |
| Formula | C₁₈H₁₅N₅O₆S₂ |