Vactosertib Hydrochloride

Supplier MedChemExpress
Product # HY-19928A-50 mg
CAS # 1352610-25-3
Pricing 50 mg, USD $816.0
Synonyms EW-7197 Hydrochloride; TEW-7197 Hydrochloride
MWt 435.88
Formula C₂₂H₁₉ClFN₇
Biological Activity Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect[1][2].
Purity 98.57%
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