Vactosertib Hydrochloride
Supplier | MedChemExpress |
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Product # | HY-19928A-50 mg |
CAS # | 1352610-25-3 |
Pricing | 50 mg, USD $816.0 |
Synonyms | EW-7197 Hydrochloride; TEW-7197 Hydrochloride |
MWt | 435.88 |
Formula | C₂₂H₁₉ClFN₇ |
Biological Activity | Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect[1][2]. |
Purity | 98.57% |