AMG 511
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-13440-25 mg |
| CAS # | 1253573-53-3 |
| Pricing | 25 mg, USD $940.0 |
| Biological Activity | AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks, with Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease. AMG 511 exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. |
| Purity | 98.81% |
| MWt | 517.58 |
| Formula | C₂₂H₂₈FN₉O₃S |