Supinoxin
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-123611-5 mg |
| CAS # | 888478-45-3 |
| Pricing | 5 mg, USD $360.0 |
| Synonyms | RX-5902 |
| MWt | 441.46 |
| Formula | C₂₂H₂₄FN₅O₄ |
| Biological Activity | Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase (P-p68) and a potent first-in-class anti-cancer agent. Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of β-catenin. Supinoxin induces cell apoptosis and inhibits growth of TNBC cancer cell lines with IC50s ranging from 10 nM to 20 nM[1][2]. |
| Purity | ≥98.0% |