Masitinib mesylate
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10209A-10 mg |
| CAS # | 1048007-93-7 |
| Pricing | 10 mg, USD $60.0 |
| Synonyms | AB-1010 mesylate |
| MWt | 594.75 |
| Formula | C₂₉H₃₄N₆O₄S₂ |
| Biological Activity | Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity[1][2][4]. |
| Purity | 99.76% |