Adipiplon
Adipiplon, also known as NG2-73 or NG273, is a new, selective gamma-amino butyric acid (GABA) partial agonist under development for the treatment of insomnia, the most common type of sleep disorder. Phase II development initial clinical results suggested that NG2-73 has the capacity to reduce sleep latency as well as increase total sleep time and sleep efficiency in insomnia patients.
| Supplier | Ace Therapeutics |
|---|---|
| Product # | SMD1297 |
| CAS # | 840486-93-3 |
| Pricing | Customizable size, Inquiry |
| Synonym | NG2-73; NG 2-73; NG-2-73; NG273; NG 273; NG-273; Adipiplon |
| Product Category | Lab-use Small Molecule Drugs |
| Chemical Formula | C18H18FN7 |
| Exact Mass | 351.1608 |
| Molecular Weight | 351.3894 |
| Elemental Analysis | C, 61.53; H, 5.16; F, 5.41; N, 27.90 |
| IUPAC/Chemical Name | 7-((2-(3-fluoropyridin-2-yl)-1H-imidazol-1-yl)methyl)-2-methyl-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidine |
| InChi Key | UAMAIHOEGLEXSV-UHFFFAOYSA-N |
| InChi Code | InChI=1S/C18H18FN7/c1-3-5-13-15(22-11-26-17(13)23-12(2)24-26)10-25-9-8-21-18(25)16-14(19)6-4-7-20-16/h4,6-9,11H,3,5,10H2,1-2H3 |
| SMILES Code | CCCC1=C(CN2C=CN=C2C3=NC=CC=C3F)N=CN4C1=NC(C)=N4 |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO, not in water |
| Shelf Life | >2 years if stored properly |
| Drug Formulation | This drug may be formulated in DMSO |
| Stock Solution Storage | 0 - 4℃ for short term (days to weeks), or -20℃ for long term (months). |
| HS Tariff Code | 2934.99.9001 |