KT5823
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-N6791-100 μg |
| CAS # | 126643-37-6 |
| Pricing | 100 μg, USD $380.0 |
| Biological Activity | KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with an Ki value of 0.23 μM, it also inhibits PKA and PKC with Ki values of 10 μM and 4 μM, respectively[1]. KT5823 is a staurosporine-related protein kinase inhibitor, increases thyroid-stimulating hormone-induced (Na+/I- symporter) NIS expression, and iodide uptake in thyroid cells[2]. KT5823 arrests cells after the G0/G1 boundary and causes increases in the levels of apoptotic DNA fragmentation[3]. |
| Purity | ≥99.0% |
| MWt | 495.53 |
| Formula | C₂₉H₂₅N₃O₅ |