Lexibulin dihydrochloride
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10498A |
| CAS # | 917111-49-0 |
| Pricing | inquire |
| Biological Activity | Lexibulin dihydrochloride (CYT-997 dihydrochloride) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo[1][2]. Lexibulin dihydrochloride induces cell apoptosis and induces mitochondrial ROS generation in GC cells[3]. |
| Synonyms | CYT-997 dihydrochloride |
| MWt | 507.46 |
| Formula | C₂₄H₃₂Cl₂N₆O₂ |