CMF019
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-103080-10 mg |
| CAS # | 1586787-08-7 |
| Pricing | 10 mg, USD $530.0 |
| Biological Activity | CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin[2]. |
| MWt | 455.61 |
| Formula | C₂₅H₃₃N₃O₃S |