WF-47-JS03
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133551-25 mg |
| Pricing | 25 mg, USD $1350.0 |
| Biological Activity | WF-47-JS03 is a potent and selective RET kinase inhibitor with IC50s of 1.7 nM and 5.3 nM for KIF5B-RET transfected Ba/F3 cells and CCDC6-RET transfected LC-2/ad lung cancer cells, respectively. WF-47-JS03 demonstrates >500-fold selectivity against kinase insert domain receptor (KDR). Effective brain penetration[1]. |
| Purity | 99.63% |
| MWt | 514.66 |
| Formula | C₃₀H₃₈N₆O₂ |