FM-479
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-131014 |
| CAS # | 2226521-64-6 |
| Pricing | inquire |
| Biological Activity | FM-479 is the negative control of FM-381 (HY-102046) and has no activity on JAK3 or other kinases[1]. FM-381 is a potent covalent reversible inhibitor of JAK3 targeting the unique Cys909. FM-381 has an IC50 of 127 pM for JAK3, with 410, 2700 and 3600-fold selectivity over JAK1, JAK2 and TYK2, respectively. |
| MWt | 442.51 |
| Formula | C₂₅H₂₆N₆O₂ |