Almonertinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-112823-25 mg |
| CAS # | 1899921-05-1 |
| Pricing | 25 mg, USD $750.0 |
| Synonyms | HS-10296 |
| MWt | 525.64 |
| Formula | C₃₀H₃₅N₇O₂ |
| Biological Activity | Almonertinib (HS-10296) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib is used for the research of the non-small cell lung cancer[1][2]. |
| Purity | 99.84% |