PD0325901
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-10254-25 mg |
| CAS # | 391210-10-9 |
| Pricing | 25 mg, USD $180.0 |
| Synonyms | PD325901 |
| MWt | 482.19 |
| Formula | C₁₆H₁₄F₃IN₂O₄ |
| Biological Activity | PD0325901 (PD325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. PD0325901 exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. PD0325901 suppresses the expression of p-ERK1/2 and induces apoptosis. PD0325901 has anti-cancer activity for a broad spectrum of human tumor xenografts[1][2][3]. |
| Purity | 99.95% |