(8α, 9S)-(+)-9-Amino-cinchonan-6'-ol, min. 90%

• Supplier: Alfa Chemistry
• Product #: ACM960050593
• CAS #: 960050-59-3
• Synonyms: (8S,9S)-9-Aminocinchonan-6'-ol;MFCD27978392;960050-59-3;(8a,9S)-(+)-9-Amino-cinchonan-6'-ol
• IUPAC Name: 4-[(S)-amino-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]methyl]quinolin-6-ol
• MolecularFormula: C19H23N3O
• MolecularWeight: 309.413g/mol
• Application:
  • 1. [2+3]-dipolar cycloaddition of cyclic enones.
  • 2. Activation of α,β-unsaturated carbonyl compounds:
  • a) vinylogous α-ketol rearrangement.
  • b) vinylogous Michael addition of β-substituted α,β-unsaturated cyclohexanones.
  • 3. Michael addition
  • a) α-nitroacetate to α,β-unsaturated ketones.
  • b) Diastereodivergent Michael addition to α-substituted, α,β-unsaturated ketones.
  • 4. α-benzoyloxylation of α-branched aldehydes.
  • 5. [4+2]-cycloadditions of β-substituted α,β-unsaturated cyclohexanones with polyconjugated malonitriles.
  • 6. Vinylogous organocascade catalysis with control of remote stereochemistry in the synthesis of spirocyclic oxindoles.