GFB-8438
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-133012-100 mg |
| CAS # | 2304549-73-1 |
| Pricing | 100 mg, USD $2250.0 |
| Biological Activity | GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model[1]. |
| Purity | 98.07% |
| MWt | 386.76 |
| Formula | C₁₆H₁₄ClF₃N₄O₂ |