DMOG

Supplier MedChemExpress
Product # HY-15893-100 mg
CAS # 89464-63-1
Pricing 100 mg, USD $132.0
Synonyms Dimethyloxallyl Glycine
MWt 175.14
Formula C₆H₉NO₅
Biological Activity DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo[1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5].
Purity ≥98.0%
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