DMOG
Supplier | MedChemExpress |
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Product # | HY-15893-100 mg |
CAS # | 89464-63-1 |
Pricing | 100 mg, USD $132.0 |
Synonyms | Dimethyloxallyl Glycine |
MWt | 175.14 |
Formula | C₆H₉NO₅ |
Biological Activity | DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1α stabilisation and accmulation in vitro and in vivo[1]. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal[2][4]. DMOG induces cell autophagy[5]. |
Purity | ≥98.0% |