PK68
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-128348-10 mM * 1 mL |
| CAS # | 2173556-69-7 |
| Pricing | 10 mM * 1 mL, USD $385.0 |
| Biological Activity | PK68 is a potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis[1]. |
| Purity | 99.92% |
| MWt | 424.52 |
| Formula | C₂₂H₂₄N₄O₃S |