Tolebrutinib
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-109192-5 mg |
| CAS # | 1971920-73-6 |
| Pricing | 5 mg, USD $400.0 |
| Synonyms | SAR442168; PRN2246 |
| MWt | 455.51 |
| Formula | C₂₆H₂₅N₅O₃ |
| Biological Activity | Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2]. |
| Purity | 98.96% |