J-113863
| Supplier | MedChemExpress |
|---|---|
| Product # | HY-103360-5 mg |
| CAS # | 353791-85-2 |
| Pricing | 5 mg, USD $160.0 |
| Biological Activity | J-113863 is a potent and selective CCR1 (CD18) antagonist with IC50 values of 0.9 nM and 5.8 nM for human and mouse CCR1 receptors, respectively. J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptors. Anti-inflammatory effect[1][2][3]. |
| Purity | ≥99.0% |
| MWt | 655.44 |
| Formula | C₃₀H₃₇Cl₂IN₂O₂ |